Unveiled in late 2009, CityCenter and its architecturally distinctive passel of properties is the Strip's newest big kahuna. While there are several hotels to choose from, die-hard gamblers are likely to gravitate toward the sleek, high-roller-friendly casinos in the 3,000-room Cosmopolitan, the most recent addition to the development. (Note: Beware that while it's technically on Las Vegas Boulevard, there's a considerable distance between many of the CityCenter buildings and the Strip itself.)

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Las Vegas Travel Guide